Job Title: Clinical Research / Medical Director
Date Posted: 04-24-2008
Job Location: New Jersey-Northern
Job Type: Full Time
Education Level: Doctorate
Work Experience: 2+ to 5 Years
Job Shift: First Shift
Yearly Salary:DOE (Depend on Experience)
Company Name: Amicus Therapeutics
Contact Information: Amicus Therapeutics   Amicus Therapeutics (
Job Description:


Amicus Therapeutics is a clinical stage biopharmaceutical company dedicated to the development
of small-molecule, orally-active drugs for the treatment of a broad range of human genetic
diseases. The company is rapidly developing its proprietary platform technology into a robust
clinical and pre-clinical pipeline. This unique technology represents a paradigm-shifting,
next generation approach to the management of genetic diseases which offers the potential to
dramatically improve treatment options for patients. 

Amicus' technology utilizes pharmacological agents to combine selectively with the diseased
protein target and reverse or reduce the effects of the gene mutation. Pharmacological
chaperones offer several advantages over competing approaches to treat genetic disorders
including oral delivery and the ability to treat difficult to reach tissues. Amicus' lead drug
candidates are for lysosomal storage diseases, a severe class of genetic diseases characterized
by serious and often life-threatening illness. 

Amicus is funded by some of the most preeminent venture capital firms in health care,
including Quaker, NEA, Prospect Ventures, Frazier Health Care Ventures, CHL Medical and Canaan
Partners. The company has built a first rate senior management team with a significant track
record of success in this industry. 

The company is headquartered in Cranbury, NJ. Amicus has a fast-paced, high-energy,
entrepreneurial team environment where employees are encouraged to be innovative and
resourceful. Amicus seeks high-caliber, talented individuals with a passion to succeed.
Additional information on the company, product pipeline, and technology is available at


Job Description:

ˇ        Together with other members of a clinical team responsible for the development and
implementation of clinical development programs studying new molecular entities for the
treatment of lysosomal storage disorders.  

ˇ        Responsible for the development of study protocols 

ˇ        Provides medical oversight to the execution of clinical studies

ˇ        Responsible for medical monitoring/reporting

ˇ        Acts as a liaison between company and clinical investigators 

ˇ        Ensures compliance with policies, regulations and healthcare laws



ˇ        MD degree required 

ˇ        A minimum of 3 years of clinical research and development experience required

ˇ        Pharmaceutical industry experience preferred

ˇ        Ability to travel required 

ˇ        Experience and/or knowledge of the management of the clinical research processes
leading to an NDA

ˇ        Thorough understanding of clinical trial design and statistics

ˇ        Excellent written and oral communication skills  

ˇ        Strong problem solving skills 

ˇ        Ability to successfully manage multiple projects and work in a fast-paced team


Amicus Therapeutics offers a competitive compensation and benefits package including, medical,
dental, 401k and stock options.


Qualified candidates please submit your résumé to:  


Fax:      609-662-2001


Amicus Therapeutics is an equal opportunity employer.
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